Modulation of calcium-binding proteins expression and cisplatin chemosensitivity by calcium chelation in human breast cancer MCF-7 cells

Cisplatin (CDDP) is currently one of the most effective FDA-approved treatments for breast cancer.Previous studies have shown that CDDP-induced cell death in human breast cancer (MCF-7) cells is associated with disruption of calcium homeostasis.However, whether the sensitivity of breast cancer cells to cisplatin is associated with Key Fob dysregula

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Comparative Study Between Tacrolimus 0.1% Ointment Versus Topical White Soft Petrolatum Jelly in the Treatment of Oral Retinoid-Induced Cheilitis

Retinoids are used topically as well as orally, and the most commonly used oral retinoids are isotretinoin and acitretin.Mucocutaneous adverse effects are frequently seen with the use of Camu Camu systemic retinoids, the most common being cheilitis, which is dose-dependent and seen in almost all patients using it.To study the comparative effect of

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Silver-doped graphene oxide nanocomposite triggers cytotoxicity and apoptosis in human hepatic normal and carcinoma cells

Daoud Ali, Saud Alarifi, Saad Alkahtani, Rafa S Almeer Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia Introduction: Graphene oxide nanoparticles have been widely used in industry and biomedical fields due to their unique physicochemical properties.However, comparative cytotoxicity of silver-doped reduced graph

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